Preclinical Services

Adita Biosys provides variety of preclinical services

  • Toxicology studies
  • Microbiology and Genotoxicity studies
  • Efficacy studies
  • Biocompatibility studies
  • Immunization studies/Antibody production
  • Biological matrices (Plasma/Serum/S9 Fractions)
  • Bioassays/pharmacopeia studies (USP, BP, EP, IP)
preclinical services

Adita Biosys Preclinical Services includes:

Acute Toxicity

  • Acute Oral / Dermal / IV / IM / SC / IP / Ocular
  • Acute Dermal Irritation / Corrosion
  • Acute Eye Irritation / Corrosion
  • Acute Infusion Studies
  • Skin Sensitization

Sub-Acute Toxicity

  • 7 / 14 Days Dose Range Finding Study
  • 14 / 28 / 90 Days Repeated Dose Studies

Sub-Chronic & Chronic Toxicity

  • 90 Days Repeated Dose Studies
  • 180 Days & above Chronic Toxicity Studies

Genetic Toxicity

  • Bacterial Reverse Mutation Test (AMES)
  • In vitro Chromosome Aberration Test
  • In vivo Bone Marrow Chromosome Aberration Test
  • In vitro Mammalian Cell Micronucleus Test

Biocompatibility Studies for Medical Devices

  • Biological Risk Assessment
  • Biocompatibility Studies
  • Cytotoxicity
  • Skin Sensitization Irritation / Intracutaneous Reactivity Test
  • Systemic Toxicity
  • Genotoxicity
  • Implantation Studies
  • Hemocompatibility Test

Bioassays

  • Menotropin FSH / LH Activity
  • Human Chorionic Gonadotropin
  • Estrogenic Activity
  • Follitropin, Residual LH Activity
  • Erythropoietin (EPO)
  • Insulin Assays
  • Rabbit Pyrogen Testing
  • Endotoxin Testing
  • Abnormal Toxicity Sterility Tests
  • Test for Microbial Contamination
  • Microbiological Assay of Antibiotics
  • Efficacy of Antimicrobial Preservation

Efficacy Studies

  • Diet Induced Obesity Studies
  • Chemical Induced Obesity Studies
  • Inflammation Studies
  • Anti-Diabetic Studies
  • Preservative Efficacy Test
  • Wound healing Studies
  • PK studies (In-life Phase)

Immunization studies

  • Polyclonal antibody production in Rats/Mice/Rabbits and Guinea Pigs

Laboratory Animals

  • Rats
  • - Wistar
  • - Sprague Dawley
  • Mice
  • - Swiss Albino
  • - C57BL/6
  • - BALB/c
  • New Zealand White Rabbits
  • Dunkin hartley Guinea Pigs
  • Hamster

Routes of Administration

  • Oral
  • Intravenous
  • Ocular
  • Dermal
  • Intradermal
  • Intramuscular
  • Intranasal
  • Intratracheal
  • Subcutaneous
  • Intraocular
  • Intracorneal
  • Infusion
  • Intravitreal
  • Intraperitoneal